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The primary function of HCG is to signal the corpus luteum to continue producing progesterone, which is vital for maintaining a pregnancy. In a medical context, it has been used to induce ovulation in women and to treat certain cases of hypogonadotropic hypogonadism in men, a condition where the testes do not produce enough testosterone due to problems with the pituitary gland. For this medical application, it is often prescribed as PREGNYL® (Human Chorionic Gonadotropin).

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